{"id":4031,"date":"2026-03-27T14:02:20","date_gmt":"2026-03-27T19:02:20","guid":{"rendered":"https:\/\/capertongillett.com\/blog\/?p=4031"},"modified":"2026-03-27T14:02:20","modified_gmt":"2026-03-27T19:02:20","slug":"the-5-worstbest-tropes-in-d2c-pharma-advertising","status":"publish","type":"post","link":"https:\/\/capertongillett.com\/blog\/the-5-worstbest-tropes-in-d2c-pharma-advertising\/","title":{"rendered":"The 5 Worstbest Tropes in D2C Pharma Advertising"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"799\" height=\"499\" src=\"https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad.jpg\" alt=\"Screenshot from a drug commercial, with black letterbox stripes across the top and bottom. It\u2019s a reasonably tight shot of the smiling face of an older white man with gray hair and extremely white teeth, grinning at a bearded man sitting next to him as an equally bearded man in the background, wearing a green hoodie and a green-and-white-striped beanie, continues to watch whatever sporting event they\u2019re watching on TV. On the lower right corner is the Pluvicto logo, and in the lower left corner are the words, \u201cPluvicto is a prescription treatment for adults with prostate-specific membrane antigen-positive metastatic castration-resistant prostate cancer (PSMA+ mCRPC) previously treated with hormone therapy and chemotherapy.\u201d\" class=\"wp-image-4036\" style=\"width:420px\" srcset=\"https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad.jpg 799w, https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad-300x187.jpg 300w, https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad-768x480.jpg 768w, https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad-384x240.jpg 384w\" sizes=\"auto, (max-width: 799px) 100vw, 799px\" \/><figcaption class=\"wp-element-caption\">Prostate-specific membrane antigen-positive metastatic castration-resistant prostate cancer previously treated with hormone therapy <em>and<\/em> chemotherapy? That could be anyone.<\/figcaption><\/figure>\n<\/div>\n\n\n<p>Why is the U.S. one of the only two countries in the entire world that allow D2C prescription drug advertising? Probably because it takes a very specific balance of healthcare needs and late-stage capitalism to decide that pressuring patients into asking their doctor for expensive name-brand medication they might not even benefit from and might not be able to afford without patient assistance they might not be eligible to get is awesome as long as you do it with a musical number.<\/p>\n\n\n\n<p>(And I say this with the greatest of affection as a person who really hopes she didn\u2019t just screw herself out of any future freelance work for pharma clients, please, I swear I have no scruples and will take your money.)<\/p>\n\n\n\n<p>All that said, without D2C drug ads, we wouldn\u2019t have some of the most bizarrely entertaining tropes in our industry. And I\u2019m not talking about farmer\u2019s market flash mobs and random bathtubs in a field. I\u2019m talking about the most encyclopedic list of horrendous side effective imaginable recited over perky royalty-free music while an elderly couple rides fixies through a flower meadow, and warnings to tell my doctor about side effects that would <em>definitely<\/em> already have me on the way to the hospital.<\/p>\n\n\n\n<p>Here are five recurring tropes that make drug advertising so darn special.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">In the \u201cevery warning label has a story\u201d category:<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Tell your doctor if you have blurred vision or a parasitic infection.<\/h4>\n\n\n\n<p>Are parasitic infections a side effect of Dupixent? No. Has parasitic infection been associated with Dupixent use? Apparently, at least with enough frequency that they felt the need to mention it, which in this case means about one tenth of one percent of patients. Should our biggest concern be that people might start experiencing abruptly blurred vision or a <em>parasitic infection<\/em> and think, \u201cNah, this seems fine,\u201d if not advised to do so by a TV commercial? I vote yes.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Dupixent Commercial (2025)\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/m2ClA4FxjjQ?start=38&#038;feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">Do not use this drug if you\u2019re allergic to this drug.<\/h4>\n\n\n\n<p>REALLY. WOW. That explains why I keep running out of EpiPens and know all the EMTs in the area by name. Now talk with me about why I keep getting hives when I eat strawberries, and whether it has anything to do with my strawberry allergy.<\/p>\n\n\n\n<p>Seriously, though, they wouldn\u2019t cram it into their very limited runtime if it wasn\u2019t actually a thing that happened, meaning there probably have been visits where the doctor and patient are discussing adding Repatha to their statin and neither mused, \u201cHey, aren\u2019t you actually <em>allergic<\/em> to Repatha?\u201d<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Repatha Commercial (2025)\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/0awOKFuet1Q?start=29&#038;feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">In the \u201ckill or cure\u201d category:<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">This drug may increase risk of a different version of the same condition.<\/h4>\n\n\n\n<p>I don\u2019t pretend to be a doctor, and I\u2019m certainly not going to try and get into a debate about the relative merits and challenges of dry vs. wet AMD. From a layperson\u2019s perspective, though, it\u2019s hard not to notice an ad mentioning that severe side effects of a drug can include a worse version of the condition you already have.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Syfovre Commercial (2025) Featuring Henry Winkler\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/xfTLpy-Ed3k?start=47&#038;feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">Common side effects include your skin turning red and peeling from your body.<\/h4>\n\n\n\n<p>No more plaque psoriasis \u2014 just redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles, skin thinning, peeling, and rash.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Duobrii\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/0IOxpVG2i1w?start=46&#038;feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">In the \u201cnumbers game\u201d category:<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">If you have HR+ HER2- metastatic breast cancer\u2026<\/h4>\n\n\n\n<p>Fun math: About 120,000 people in the U.S. have that specific kind of cancer. If Pfizer is going to drop $200k on 0:60 broadcast ad space, that means they\u2019re spending $1.66 per patient to try to talk them into taking Ibrance, and it strikes me that D2C advertising in this case might not be as efficient as throwing a couple more pens and branded Post-Its at oncologists.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Ibrance Commercial (2025, *Updated)\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/wBuQ8K8bnN4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">If you have PSMA+ mCRPC prostate cancer that hasn\u2019t responded to hormone therapy or chemotherapy\u2026<\/h4>\n\n\n\n<p>At some point, your best budget bet is just going to be, \u201cHey, Keith. Keith Watkins, Saratoga Springs. Yeah, hi. Talk to Dr. Woodson about Pluvicto.\u201d<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Pluvicto Commercial (2024 &amp; 2025)\" width=\"693\" height=\"390\" src=\"https:\/\/www.youtube.com\/embed\/b-qkb0SYP0o?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">In the \u201chow about you tell <em>me<\/em> if I have cancer\u201d category:<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Tell your doctor if you have cancer.<\/h4>\n\n\n\n<p>\u2026 Your doctor should know. If you have cancer, your doctor should <em>definitely<\/em> know about it, and if you\u2019re sitting around thinking, \u201cI should tell Dr. So-and-So about my CANCER while we\u2019re discussing this drug,\u201d you have the WRONG DOCTOR. Whether or not you\u2019d benefit from whatever drug is being shilled to you, I hereby Rx you A DIFFERENT DOCTOR.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Stay healthy, y\u2019all.<\/h2>\n\n\n\n<p>And if you\u2019re worried that reading my blog might lead to redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles, skin thinning, peeling, rash, nausea, restlessness, fatigue, flulike symptoms, weight loss, weight gain, hypertension, depression, anxiety, dizziness, sleepiness, swelling of the tongue or throat, headache, diarrhea, sexual dysfunction, and wet AMD\u2026&nbsp;<\/p>\n\n\n\n<p>I wouldn\u2019t worry about it. Stress isn\u2019t good for you.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Why is the U.S. one of the only two countries in the entire world that allow D2C prescription drug advertising? Probably because it takes a very specific balance of healthcare &hellip;<\/p>\n","protected":false},"author":1,"featured_media":4036,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[109,72],"class_list":["post-4031","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-advertising-irl","tag-drug-advertising","tag-tv"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The 5 Worstbest Tropes in D2C Pharma Advertising - Caperton Gillett | The Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/capertongillett.com\/blog\/the-5-worstbest-tropes-in-d2c-pharma-advertising\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The 5 Worstbest Tropes in D2C Pharma Advertising - Caperton Gillett | The Blog\" \/>\n<meta property=\"og:description\" content=\"Why is the U.S. one of the only two countries in the entire world that allow D2C prescription drug advertising? Probably because it takes a very specific balance of healthcare &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/capertongillett.com\/blog\/the-5-worstbest-tropes-in-d2c-pharma-advertising\/\" \/>\n<meta property=\"og:site_name\" content=\"Caperton Gillett | The Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/capertongcreative\/\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/capertongcreative\" \/>\n<meta property=\"article:published_time\" content=\"2026-03-27T19:02:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/capertongillett.com\/blog\/wp-content\/uploads\/2026\/03\/pluvicto-ad.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"799\" \/>\n\t<meta property=\"og:image:height\" content=\"499\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Caper\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@CapeGCreative\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Caper\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/\"},\"author\":{\"name\":\"Caper\",\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/#\\\/schema\\\/person\\\/a8b294ce5e33f2905e82f8435c3650c4\"},\"headline\":\"The 5 Worstbest Tropes in D2C Pharma Advertising\",\"datePublished\":\"2026-03-27T19:02:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/\"},\"wordCount\":917,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/pluvicto-ad.jpg\",\"keywords\":[\"Drug advertising\",\"TV\"],\"articleSection\":[\"Advertising IRL\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/\",\"url\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/\",\"name\":\"The 5 Worstbest Tropes in D2C Pharma Advertising - Caperton Gillett | The Blog\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/pluvicto-ad.jpg\",\"datePublished\":\"2026-03-27T19:02:20+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/the-5-worstbest-tropes-in-d2c-pharma-advertising\\\/#primaryimage\",\"url\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/pluvicto-ad.jpg\",\"contentUrl\":\"https:\\\/\\\/capertongillett.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/03\\\/pluvicto-ad.jpg\",\"width\":799,\"height\":499,\"caption\":\"Screenshot from a drug commercial, with black letterbox stripes across the top and bottom. 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